Iopamidol + Metformin Interaction
Majorinteraction on record
Description
Iodinated contrast agents increase risk of metformin-induced lactic acidosis, possibly by worsening renal function. Stop metformin at time of or prior to iopamidol injection in patients with eGFR 30-60 mL/min/1.73 m² or history of hepatic impairment, alcoholism, or heart failure.
Mechanism
Worsening renal function
Source: NLP:iopamidol