Iron Chelators + Marnetegragene Autotemcel Interaction
Majorinteraction on record
Description
Discontinue at least 7 days prior to myeloablative conditioning initiation. Avoid myelosuppressive iron chelators for 6 months after ZYNTEGLO infusion. Consider non-myelosuppressive alternatives or phlebotomy.
Mechanism
Drug-drug interactions with myeloablative conditioning agents; some iron chelators are myelosuppressive
Source: NLP:betibeglogene autotemcel