HomeItraconazoleItraconazole + Emtricitabine Rilpivirine And Tenofovir Disoproxil Fumarate

Does Itraconazole Interact with Emtricitabine Rilpivirine And Tenofovir Disoproxil Fumarate?

Itraconazole and Emtricitabine Rilpivirine And Tenofovir Disoproxil Fumarate have a unknown drug interaction according to U.S. FDA drug labeling data. Azole Antifungal Agents: fluconazole itraconazole ketoconazole posaconazole voriconazole ↑ RPV , This interaction study has been performed with a dose higher than the recommended dose for RPV assessing the maximal effect on the coadministered drug. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Unknown
Itraconazole Class
Azole Antifungal
Emtricitabine Rilpivirine And Tenofovir Disoproxil Fumarate Class
Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor
Management
Consult your pharmacist
Data Source
U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Itraconazole and your doctor is considering prescribing Emtricitabine Rilpivirine And Tenofovir Disoproxil Fumarate (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Never stop or change either medication without first consulting your healthcare provider
💊 Itraconazole(Sporanox)+💊 Emtricitabine Rilpivirine And Tenofovir Disoproxil Fumarate(Complera)

Severity & Interaction Details

ℹ️
unknown
Interaction documented — severity unclassified
The FDA label notes an interaction but the severity is not classified in our dataset.
Severity scale
MinorContra
On record
Yes
Drug A class
Azole Antifungal
Drug B class
Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor
Source
FDA drug label - emtricitabine, rilpivirine and tenofovir disoproxil fumarate

What this means in plain English

Azole Antifungal Agents: fluconazole itraconazole ketoconazole posaconazole voriconazole ↑ RPV , This interaction study has been performed with a dose higher than the recommended dose for RPV assessing the maximal effect on the coadministered drug.

About Itraconazole and Emtricitabine Rilpivirine And Tenofovir Disoproxil Fumarate

Itraconazole is an Azole Antifungal, while Emtricitabine Rilpivirine And Tenofovir Disoproxil Fumarate is a Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor. You may recognize them by the brand names Sporanox and Complera. Both medications are taken by mouth. Both Itraconazole and Emtricitabine Rilpivirine And Tenofovir Disoproxil Fumarate carry an FDA boxed warning — the agency's most serious safety designation.

Recent research & FDA safety updates

Live

Auto-aggregated from PubMed E-utilities and FDA safety data.

PubMed
Pharmacogenomics of current antiretroviral drugs.about Emtricitabine Rilpivirine And Tenofovir Disoproxil Fumarate · 2026-03
PubMed
Antiretroviral Treatment Switch Among Treatment-Experienced People with HIV.about Emtricitabine Rilpivirine And Tenofovir Disoproxil Fumarate · 2026-02

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Data integrity: Every interaction shown is extracted directly from official U.S. FDA drug labeling via openFDA and the U.S. National Library of Medicine (NIH) — no interactions are invented, inferred, or manually edited. Maintained by CheckDrugInteractions.com. See our methodology or report a correction at support@checkdruginteractions.com.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.