Itraconazole + Gemfibrozil Interaction
Unknowninteraction on record
Description
In the same study, gemfibrozil (600 mg twice daily for 3 days) + itraconazole (200 mg in the morning and 100 mg in the evening at Day 1, then 100 mg twice daily at Day 2–3) resulted in a 19.4-(range 12.9- to 24.7-fold) higher repaglinide AUC and a 70.4 fold (range 42.9-to 119.2-fold) higher repaglinide plasma concentration 7 hours after the dose. In addition, gemfibrozil alone or gemfibrozil + itraconazole prolonged the hypoglycemic effects of repaglinide.
Source: FDA drug label - gemfibrozil