Lamivudine And Tenofovir Disoproxil Fumarate + Velpatasvir Interaction

Moderateinteraction on record

Description

7.3 Hepatitis C Antiviral Agents Coadministration of TDF, a component of CIMDUO, and EPCLUSA ® (sofosbuvir/velpatasvir) or HARVONI ® (ledipasvir/sofosbuvir) has been shown to increase tenofovir exposure [see Clinical Pharmacology (12.3) ] . In patients receiving TDF concomitantly with sofosbuvir/velpatasvir, monitor for adverse reactions associated with TDF.

Source: FDA drug label - lamivudine and tenofovir disoproxil fumarate