Home›Ledipasvir And Sofosbuvir›Ledipasvir And Sofosbuvir + Tipranavir

Does Ledipasvir And Sofosbuvir Interact with Tipranavir?

Ledipasvir And Sofosbuvir and Tipranavir have a unknown drug interaction according to U.S. FDA drug labeling data. tipranavir/ritonavir ↓ ledipasvir ↓ sofosbuvir Coadministration of HARVONI with tipranavir/ritonavir is expected to decrease the concentration of ledipasvir and sofosbuvir, leading to reduced therapeutic effect of HARVONI. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Unknown
Ledipasvir And Sofosbuvir Class
Hepatitis C Virus NS5A Inhibitor
Tipranavir Class
Protease Inhibitor
Management
Consult your pharmacist
Data Source
U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Ledipasvir And Sofosbuvir and your doctor is considering prescribing Tipranavir (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Never stop or change either medication without first consulting your healthcare provider
💊 Ledipasvir And Sofosbuvir(Harvoni)+💊 Tipranavir(Aptivus)

Severity & Interaction Details

ℹ️
unknown
Interaction documented — severity unclassified
The FDA label notes an interaction but the severity is not classified in our dataset.
Severity scale
MinorContra
On record
Yes
Drug A class
Hepatitis C Virus NS5A Inhibitor
Drug B class
Protease Inhibitor
Source
FDA drug label - ledipasvir and sofosbuvir

What this means in plain English

tipranavir/ritonavir ↓ ledipasvir ↓ sofosbuvir Coadministration of HARVONI with tipranavir/ritonavir is expected to decrease the concentration of ledipasvir and sofosbuvir, leading to reduced therapeutic effect of HARVONI.

About Ledipasvir And Sofosbuvir and Tipranavir

Ledipasvir And Sofosbuvir is a Hepatitis C Virus NS5A Inhibitor, while Tipranavir is a Protease Inhibitor. You may recognize them by the brand names Harvoni and Aptivus. Both medications are taken by mouth. Both Ledipasvir And Sofosbuvir and Tipranavir carry an FDA boxed warning — the agency's most serious safety designation.

Share this result:

WhatsAppText / SMSEmail
Also share on:XFacebook
Add more drugs
Check Ledipasvir And Sofosbuvir and Tipranavir against your full medication list

Most patients take more than two medications. CDI checks every pair across up to 20 drugs simultaneously — including OTCs and common supplements.

Add more drugs →
Data integrity: Every interaction shown is extracted directly from official U.S. FDA drug labeling via openFDA and the U.S. National Library of Medicine (NIH) — no interactions are invented, inferred, or manually edited. Maintained by CheckDrugInteractions.com. See our methodology or report a correction at support@checkdruginteractions.com.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.