HomeLeucine Phenylalanine Lysine Methionine Isoleucine Valine HiLeucine Phenylalanine Lysine Methionine Isoleucine Valine Hi + Angiotensin Ii

Does Leucine Phenylalanine Lysine Methionine Isoleucine Valine Hi Interact with Angiotensin Ii?

Leucine Phenylalanine Lysine Methionine Isoleucine Valine Hi and Angiotensin Ii have a moderate drug interaction according to U.S. FDA drug labeling data. Angiotensin II receptor antagonists may increase risk of hyperkalemia when used with CLINIMIX E due to its potassium content; administer with caution. The mechanism involves additive hyperkalemia risk. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Moderate
Leucine Phenylalanine Lysine Methionine Isoleucine Valine Hi Class
Amino Acid
Angiotensin Ii Class
Vasoconstrictor
Management
Monitor for effects
Data Source
U.S. FDA via OpenFDA

How This Interaction Works

The interaction between Leucine Phenylalanine Lysine Methionine Isoleucine Valine Hi and Angiotensin Ii occurs because additive hyperkalemia risk. Clinically, this means angiotensin ii receptor antagonists may increase risk of hyperkalemia when used with clinimix e due to its potassium content; administer with caution. This is classified as a moderate interaction. While it may not require stopping either medication, your healthcare provider should be aware you are taking both so they can monitor for potential effects and adjust treatment if necessary.

What To Tell Your Doctor or Pharmacist

If you are taking Leucine Phenylalanine Lysine Methionine Isoleucine Valine Hi and your doctor is considering prescribing Angiotensin Ii (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Ask whether any dosage adjustments are needed
  • Never stop or change either medication without first consulting your healthcare provider
💊 Leucine Phenylalanine Lysine Methionine Isoleucine Valine Hi(Clinimix E)+💊 Angiotensin Ii(Giapreza)

Severity & Interaction Details

🟡
moderate
Be aware — moderate interaction
Documented interaction with manageable risk. May require dose adjustment or monitoring.
Severity scale
MinorContra
On record
Yes
Drug A class
Amino Acid
Drug B class
Vasoconstrictor
Source
NLP:leucine, phenylalanine, lysine, methionine, isoleucine, valine, histidine, threonine, tryptophan, alanine, glycine, arginine, proline, serine, tyrosine, dibasic potassium phosphate, magnesium chloride, sodium chloride, calcium chloride, dextrose

What this means in plain English

Angiotensin II receptor antagonists may increase risk of hyperkalemia when used with CLINIMIX E due to its potassium content; administer with caution.

About Leucine Phenylalanine Lysine Methionine Isoleucine Valine Hi and Angiotensin Ii

Leucine Phenylalanine Lysine Methionine Isoleucine Valine Hi is an Amino Acid, while Angiotensin Ii is a Vasoconstrictor. You may recognize them by the brand names Clinimix E and Giapreza. Both medications are given by intravenous (IV) infusion.

What the FDA label says

"Additive hyperkalemia risk"

📖 Source: NLP:leucine, phenylalanine, lysine, methionine, isoleucine, valine, histidine, threonine, tryptophan, alanine, glycine, arginine, proline, serine, tyrosine, dibasic potassium phosphate, magnesium chloride, sodium chloride, calcium chloride, dextrose

Recent research & FDA safety updates

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Auto-aggregated from PubMed E-utilities and FDA safety data.

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Data integrity: Every interaction shown is extracted directly from official U.S. FDA drug labeling via openFDA and the U.S. National Library of Medicine (NIH) — no interactions are invented, inferred, or manually edited. Maintained by CheckDrugInteractions.com. See our methodology or report a correction at support@checkdruginteractions.com.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.