Does Linezolid Interact with Atropa Belladonna And Opium?
CDI records a contraindicated classification for Linezolid and Atropa Belladonna And Opium. The stored summary is: MAOI-like interaction may manifest as serotonin syndrome or opioid toxicity. Use not recommended; avoid within 14 days of stopping treatment. The mechanism involves monoamine oxidase inhibition with serotonergic and opioid effects. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Contraindicated
- Linezolid Class
- Oxazolidinone Antibacterial
- Management
- Do not take together
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Monoamine oxidase inhibition with serotonergic and opioid effects
What To Tell Your Doctor or Pharmacist
If you are taking Linezolid and your doctor is considering prescribing Atropa Belladonna And Opium (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask about alternative medications that do not interact with your current regimen
- Ask how frequently you should be monitored while these are co-prescribed
- Never stop or change either medication without first consulting your healthcare provider