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Does Lithium Interact with Bismuth Subcitrate Potassium Metronidazole And Tetracycline ?

Lithium and Bismuth Subcitrate Potassium Metronidazole And Tetracycline have a major drug interaction according to U.S. FDA drug labeling data. Increased lithium serum concentrations; measure serum lithium and serum creatinine concentrations during therapy. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Major
Bismuth Subcitrate Potassium Metronidazole And Tetracycline Class
Nitroimidazole Antimicrobial
Management
Close medical supervision required
Data Source
U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Lithium and your doctor is considering prescribing Bismuth Subcitrate Potassium Metronidazole And Tetracycline (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Ask how frequently you should be monitored while these are co-prescribed
  • Ask whether any dosage adjustments are needed
  • Never stop or change either medication without first consulting your healthcare provider
💊 Lithium(Lithium)+💊 Bismuth Subcitrate Potassium Metronidazole And Tetracycline (Pylera)

Severity & Interaction Details

⚠️
major
Use with caution — major interaction
Serious risk of clinically significant harm. Generally avoid; if used, monitor closely.
Severity scale
MinorContra
On record
Yes
Drug A class
—
Drug B class
Nitroimidazole Antimicrobial
Source
NLP:bismuth subcitrate potassium, metronidazole and tetracycline hydrochloride

What this means in plain English

Increased lithium serum concentrations; measure serum lithium and serum creatinine concentrations during therapy.

About Lithium and Bismuth Subcitrate Potassium Metronidazole And Tetracycline

Bismuth Subcitrate Potassium Metronidazole And Tetracycline is a Nitroimidazole Antimicrobial. Bismuth Subcitrate Potassium Metronidazole And Tetracycline is also sold under the brand name Pylera. Both medications are taken by mouth. Both Lithium and Bismuth Subcitrate Potassium Metronidazole And Tetracycline carry an FDA boxed warning — the agency's most serious safety designation.

Recent research & FDA safety updates

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Data integrity: Every interaction shown is extracted directly from official U.S. FDA drug labeling via openFDA and the U.S. National Library of Medicine (NIH) — no interactions are invented, inferred, or manually edited. Maintained by CheckDrugInteractions.com. See our methodology or report a correction at support@checkdruginteractions.com.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.