Lorazepam + Olanzapine Interaction
Unknowninteraction on record
Description
( 7.2 ) Lorazepam (IM): Increased somnolence with IM olanzapine. Lorazepam (IM) — Administration of intramuscular lorazepam (2 mg) 1 hour after intramuscular olanzapine for injection (5 mg) did not significantly affect the pharmacokinetics of olanzapine, unconjugated lorazepam, or total lorazepam. However, this co-administration of intramuscular lorazepam and intramuscular olanzapine for injection added to the somnolence observed with either drug alone [see Warnings and Precautions ( 5.7 )] .
Source: FDA drug label - olanzapine