Does Magnesium Sulfate In Dextrose Interact with Amphotericin B?
CDI records a moderate classification for Magnesium Sulfate In Dextrose and Amphotericin B. The stored summary is: Amphotericin B induces renal losses of magnesium, potentially leading to hypomagnesemia. The mechanism involves drug-induced renal losses of magnesium. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Moderate
- Amphotericin B Class
- Lipid-based Polyene Antifungal
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Drug-induced renal losses of magnesium
What To Tell Your Doctor or Pharmacist
If you are taking Magnesium Sulfate In Dextrose and your doctor is considering prescribing Amphotericin B (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider