Does Metoprolol Tartrate And Hydrochlorothiazide Interact with Methyldopa?
Metoprolol Tartrate And Hydrochlorothiazide and Methyldopa have a unknown drug interaction according to U.S. FDA drug labeling data. Rare reports in literature of hemolytic anemia occurring with concomitant use of hydrochlorothiazide and methyldopa. The mechanism involves unknown mechanism of hemolytic anemia. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Unknown
- Metoprolol Tartrate And Hydrochlorothiazide Class
- Thiazide Diuretic
- Management
- Consult your pharmacist
- Data Source
- U.S. FDA via OpenFDA
How This Interaction Works
The interaction between Metoprolol Tartrate And Hydrochlorothiazide and Methyldopa occurs because unknown mechanism of hemolytic anemia. Clinically, this means rare reports in literature of hemolytic anemia occurring with concomitant use of hydrochlorothiazide and methyldopa.
What To Tell Your Doctor or Pharmacist
If you are taking Metoprolol Tartrate And Hydrochlorothiazide and your doctor is considering prescribing Methyldopa (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Never stop or change either medication without first consulting your healthcare provider