Home›Metronidazole Vaginal Gel 13›Metronidazole Vaginal Gel 13 + Metronidazole

Does Metronidazole Vaginal Gel 13 Interact with Metronidazole?

Metronidazole Vaginal Gel 13 and Metronidazole have a unknown drug interaction according to U.S. FDA drug labeling data. 7 DRUG INTERACTIONS The intravaginal administration of a single dose of metronidazole vaginal gel results in lower systemic exposure to metronidazole that is approximately 2% to 4% of that achieved following oral administration of 500 mg metronidazole tablets [see Clinical Pharmacology ( 12.3 )]. The following drug interactions were reported for oral metronidazole. • Warfarin and other coumarin anticoagulants: Prolonged anticoagulant effects of warfarin and other coumarin anticoagulants have been reported with co-administration of oral metronidazole. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Unknown
Metronidazole Vaginal Gel 13 Class
Nitroimidazole Antimicrobial
Metronidazole Class
Nitroimidazole Antimicrobial
Management
Consult your pharmacist
Data Source
U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Metronidazole Vaginal Gel 13 and your doctor is considering prescribing Metronidazole (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Never stop or change either medication without first consulting your healthcare provider
💊 Metronidazole Vaginal Gel 13(Metronidazole Vaginal Gel)+💊 Metronidazole(Rosadan)

Severity & Interaction Details

ℹ️
unknown
Interaction documented — severity unclassified
The FDA label notes an interaction but the severity is not classified in our dataset.
Severity scale
MinorContra
On record
Yes
Drug A class
Nitroimidazole Antimicrobial
Drug B class
Nitroimidazole Antimicrobial
Source
FDA drug label - metronidazole vaginal gel, 1.3 %

What this means in plain English

7 DRUG INTERACTIONS The intravaginal administration of a single dose of metronidazole vaginal gel results in lower systemic exposure to metronidazole that is approximately 2% to 4% of that achieved following oral administration of 500 mg metronidazole tablets [see Clinical Pharmacology ( 12.3 )]. The following drug interactions were reported for oral metronidazole. • Warfarin and other coumarin anticoagulants: Prolonged anticoagulant effects of warfarin and other coumarin anticoagulants have been reported with co-administration of oral metronidazole.

About Metronidazole Vaginal Gel 13 and Metronidazole

Metronidazole Vaginal Gel 13 and Metronidazole both belong to the Nitroimidazole Antimicrobial class. Metronidazole is also sold under the brand name Rosadan. Metronidazole Vaginal Gel 13 is given vaginally, whereas Metronidazole is applied to the skin. Metronidazole additionally carries an FDA boxed warning, the FDA's strongest safety alert.

Share this result:

WhatsAppText / SMSEmail
Also share on:XFacebook
Add more drugs
Check Metronidazole Vaginal Gel 13 and Metronidazole against your full medication list

Most patients take more than two medications. CDI checks every pair across up to 20 drugs simultaneously — including OTCs and common supplements.

Add more drugs →
Data integrity: Every interaction shown is extracted directly from official U.S. FDA drug labeling via openFDA and the U.S. National Library of Medicine (NIH) — no interactions are invented, inferred, or manually edited. Maintained by CheckDrugInteractions.com. See our methodology or report a correction at support@checkdruginteractions.com.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.