Does Midazolam Interact with Tecovirimat Monohydrate?
Midazolam and Tecovirimat Monohydrate have a moderate drug interaction according to U.S. FDA drug labeling data. CNS Depressant: Midazolam b ↓ midazolam Monitor for effectiveness of midazolam. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Moderate
- Midazolam Class
- Benzodiazepine
- Tecovirimat Monohydrate Class
- Orthopoxvirus VP37 Envelope Wrapping Protein Inhibitor
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
What To Tell Your Doctor or Pharmacist
If you are taking Midazolam and your doctor is considering prescribing Tecovirimat Monohydrate (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider