HomeMidazolam Injection 10 MgMidazolam Injection 10 Mg + Erythromycin

Does Midazolam Injection 10 Mg Interact with Erythromycin?

Midazolam Injection 10 Mg and Erythromycin have a moderate drug interaction according to U.S. FDA drug labeling data. Cytochrome P450-3A4 Inhibitors Caution is advised when Midazolam Injection is administered concomitantly with drugs that are known to inhibit the P450-3A4 enzyme system (e.g., cimetidine, erythromycin, diltiazem, verapamil, ketoconazole, and itraconazole). Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Moderate
Midazolam Injection 10 Mg Class
Benzodiazepine
Erythromycin Class
Macrolide
Management
Monitor for effects
Data Source
U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Midazolam Injection 10 Mg and your doctor is considering prescribing Erythromycin (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Ask whether any dosage adjustments are needed
  • Never stop or change either medication without first consulting your healthcare provider
💊 Midazolam Injection 10 Mg(N/A)+💊 Erythromycin(Benzamycin)

Severity & Interaction Details

🟡
moderate
Be aware — moderate interaction
Documented interaction with manageable risk. May require dose adjustment or monitoring.
Severity scale
MinorContra
On record
Yes
Drug A class
Benzodiazepine
Drug B class
Macrolide
Source
FDA drug label - midazolam injection, 10 mg

What this means in plain English

Cytochrome P450-3A4 Inhibitors Caution is advised when Midazolam Injection is administered concomitantly with drugs that are known to inhibit the P450-3A4 enzyme system (e.g., cimetidine, erythromycin, diltiazem, verapamil, ketoconazole, and itraconazole).

About Midazolam Injection 10 Mg and Erythromycin

Midazolam Injection 10 Mg is a Benzodiazepine, while Erythromycin is a Macrolide. You may recognize them by the brand names N/A and Benzamycin. Midazolam Injection 10 Mg is given by intramuscular injection, whereas Erythromycin is taken by mouth. Midazolam Injection 10 Mg additionally carries an FDA boxed warning, the FDA's strongest safety alert.

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Data integrity: Every interaction shown is extracted directly from official U.S. FDA drug labeling via openFDA and the U.S. National Library of Medicine (NIH) — no interactions are invented, inferred, or manually edited. Maintained by CheckDrugInteractions.com. See our methodology or report a correction at support@checkdruginteractions.com.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.