Moderate To Strong Cyp2c19 Inducers + Mavacamten Interaction
Contraindicatedinteraction on record
Description
Concomitant use decreases mavacamten exposure and may reduce efficacy. Risk of heart failure may increase upon discontinuation. Contraindicated.
Mechanism
CYP2C19 induction decreases mavacamten plasma concentrations
Source: NLP:mavacamten