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Does Monoamine Oxidase Inhibitors Maois Interact with Acetaminophen Chlorpheniramine Maleate Dextromethorphan Hbr ?

Monoamine Oxidase Inhibitors Maois and Acetaminophen Chlorpheniramine Maleate Dextromethorphan Hbr have a contraindicated drug interaction according to U.S. FDA drug labeling data. Do not use if currently taking an MAOI or within 2 weeks of stopping MAOI therapy. Includes drugs for depression, psychiatric/emotional conditions, or Parkinson's disease. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Contraindicated
Acetaminophen Chlorpheniramine Maleate Dextromethorphan Hbr Class
Expectorant
Management
Do not take together
Data Source
U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Monoamine Oxidase Inhibitors Maois and your doctor is considering prescribing Acetaminophen Chlorpheniramine Maleate Dextromethorphan Hbr (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Ask about alternative medications that do not interact with your current regimen
  • Ask how frequently you should be monitored while these are co-prescribed
  • Never stop or change either medication without first consulting your healthcare provider
💊 Monoamine Oxidase Inhibitors Maois+💊 Acetaminophen Chlorpheniramine Maleate Dextromethorphan Hbr (Broncochem Expectorant Ii)

Severity & Interaction Details

⛔
contraindicated
Avoid this combination
FDA labeling lists this pair as contraindicated. The risk outweighs the benefit in nearly all cases.
Severity scale
MinorContra
On record
Yes
Drug A class
—
Drug B class
Expectorant
Source
NLP:acetaminophen-chlorpheniramine maleate-dextromethorphan hbr-guaifenesin-phenylephrine hcl

What this means in plain English

Do not use if currently taking an MAOI or within 2 weeks of stopping MAOI therapy. Includes drugs for depression, psychiatric/emotional conditions, or Parkinson's disease.

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Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine. For informational purposes only. Always consult your pharmacist or physician.