Does Multivitaminmineral Interact with Paricalcitol?
Multivitaminmineral and Paricalcitol have a moderate drug interaction according to U.S. FDA drug labeling data. May affect fat absorption and reduce paricalcitol absorption. Separate dosing by at least 1 hour before or 4-6 hours after. The mechanism involves interference with intestinal absorption of paricalcitol. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Moderate
- Multivitaminmineral Class
- Vitamin B12
- Paricalcitol Class
- Vitamin D2 Analog
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
How This Interaction Works
The interaction between Multivitaminmineral and Paricalcitol occurs because interference with intestinal absorption of paricalcitol. Clinically, this means may affect fat absorption and reduce paricalcitol absorption. separate dosing by at least 1 hour before or 4-6 hours after. This is classified as a moderate interaction. While it may not require stopping either medication, your healthcare provider should be aware you are taking both so they can monitor for potential effects and adjust treatment if necessary.
What To Tell Your Doctor or Pharmacist
If you are taking Multivitaminmineral and your doctor is considering prescribing Paricalcitol (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider