Does Nonselective Beta Adrenergic Antagonists Interact with Asprin And Extended Release Dipyridamole?
Nonselective Beta Adrenergic Antagonists and Asprin And Extended Release Dipyridamole have a moderate drug interaction according to U.S. FDA drug labeling data. Hypotensive effects of beta blockers may be diminished by aspirin due to inhibition of renal prostaglandins, leading to decreased renal blood flow and salt/fluid retention. The mechanism involves inhibition of renal prostaglandins. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Moderate
- Asprin And Extended Release Dipyridamole Class
- Nonsteroidal Anti-inflammatory Drug
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
How This Interaction Works
The interaction between Nonselective Beta Adrenergic Antagonists and Asprin And Extended Release Dipyridamole occurs because inhibition of renal prostaglandins. Clinically, this means hypotensive effects of beta blockers may be diminished by aspirin due to inhibition of renal prostaglandins, leading to decreased renal blood flow and salt/fluid retention. This is classified as a moderate interaction. While it may not require stopping either medication, your healthcare provider should be aware you are taking both so they can monitor for potential effects and adjust treatment if necessary.
What To Tell Your Doctor or Pharmacist
If you are taking Nonselective Beta Adrenergic Antagonists and your doctor is considering prescribing Asprin And Extended Release Dipyridamole (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider