Nsaids + Irbesartan Interaction
Majorinteraction on record
Description
Coadministration may result in deterioration of renal function, including possible acute renal failure, especially in elderly, volume-depleted, or renally compromised patients. Antihypertensive effect may be attenuated.
Mechanism
Reduced renal perfusion and antagonism of antihypertensive effect
Source: NLP:irbesartan