Nsaids + Losartan Potassium Interaction
Majorinteraction on record
Description
May result in deterioration of renal function, including possible acute renal failure, especially in elderly, volume-depleted, or renally impaired patients. Antihypertensive effect may be attenuated.
Mechanism
COX inhibition impairs renal function and reduces antihypertensive efficacy
Source: NLP:losartan potassium