Does Octreotide Acetate Interact with Cyclosporine?
CDI records a major classification for Octreotide Acetate and Cyclosporine. The stored summary is: Octreotide may decrease blood levels of cyclosporine and result in transplant rejection due to alterations in nutrient absorption. The mechanism involves altered nutrient absorption affecting oral drug absorption. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Major
- Cyclosporine Class
- Calcineurin Inhibitor Immunosuppressant
- Management
- Close medical supervision required
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Altered nutrient absorption affecting oral drug absorption
What To Tell Your Doctor or Pharmacist
If you are taking Octreotide Acetate and your doctor is considering prescribing Cyclosporine (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask how frequently you should be monitored while these are co-prescribed
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider