Does Octreotide Acetate Interact with Sandostatin?
Octreotide Acetate and Sandostatin have a unknown drug interaction according to U.S. FDA drug labeling data. 7 DRUG INTERACTIONS The following drugs require monitoring and possible dose adjustment when used with Sandostatin Injection : Cyclosporine, insulin, oral hypoglycemic agents, beta-blockers, and bromocriptine. ( 7 ) Lutetium Lu 177 Dotatate Injection : Discontinue Sandostatin Injection at least 24 hours prior to each lutetium Lu 177 dotatate dose. Concomitant administration of Sandostatin Injection with cyclosporine may decrease blood levels of cyclosporine and result in transplant rejection. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Unknown
- Management
- Consult your pharmacist
- Data Source
- U.S. FDA via OpenFDA
What To Tell Your Doctor or Pharmacist
If you are taking Octreotide Acetate and your doctor is considering prescribing Sandostatin (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Never stop or change either medication without first consulting your healthcare provider