Opioid Analgesics + Promethazine Hydrochloride And Phenylephrine Hydrochloride Interaction

Moderateinteraction on record

Description

Promethazine may increase, prolong, or intensify sedative action; dose should be reduced by one-quarter to one-half.

Mechanism

CNS depression potentiation

Source: NLP:promethazine hydrochloride and phenylephrine hydrochloride