Oral Anticoagulants + Fenofibric Acid Interaction

Majorinteraction on record

Description

Fibrates may potentiate coumarin anticoagulant effects with prolongation of PT/INR. Reduce anticoagulant dosage and monitor PT/INR frequently to prevent bleeding complications.

Mechanism

Potentiation of coumarin-type anticoagulant effects with PT/INR prolongation

Source: NLP:fenofibric acid