Home›Pimozide›Pimozide + Escitalopram Oxalate

Does Pimozide Interact with Escitalopram Oxalate?

Pimozide and Escitalopram Oxalate have a contraindicated drug interaction according to U.S. FDA drug labeling data. Concomitant use increases plasma concentrations of pimozide and may increase risk of QT prolongation and ventricular arrhythmias. Escitalopram oxalate is contraindicated. The mechanism involves increased pimozide plasma concentrations. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Contraindicated
Pimozide Class
Typical Antipsychotic
Management
Do not take together
Data Source
U.S. FDA via OpenFDA

How This Interaction Works

The interaction between Pimozide and Escitalopram Oxalate occurs because increased pimozide plasma concentrations. Clinically, this means concomitant use increases plasma concentrations of pimozide and may increase risk of qt prolongation and ventricular arrhythmias. escitalopram oxalate is contraindicated. Because of the severity of this interaction, these medications are contraindicated — meaning they should not be taken together under any circumstances. If you are currently taking both, contact your healthcare provider immediately to discuss alternatives.

What To Tell Your Doctor or Pharmacist

If you are taking Pimozide and your doctor is considering prescribing Escitalopram Oxalate (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Ask about alternative medications that do not interact with your current regimen
  • Ask how frequently you should be monitored while these are co-prescribed
  • Never stop or change either medication without first consulting your healthcare provider
💊 Pimozide(Pimozide)+💊 Escitalopram Oxalate(Escitalopram Oxalate)

Severity & Interaction Details

⛔
contraindicated
Avoid this combination
FDA labeling lists this pair as contraindicated. The risk outweighs the benefit in nearly all cases.
Severity scale
MinorContra
On record
Yes
Drug A class
Typical Antipsychotic
Drug B class
—
Source
NLP:escitalopram oxalate

What this means in plain English

Concomitant use increases plasma concentrations of pimozide and may increase risk of QT prolongation and ventricular arrhythmias. Escitalopram oxalate is contraindicated.

What the FDA label says

"Increased pimozide plasma concentrations"

📖 Source: NLP:escitalopram oxalate

Share this result:

WhatsAppText / SMSEmail
Also share on:XFacebook
Add more drugs
Check Pimozide and Escitalopram Oxalate against your full medication list

Most patients take more than two medications. CDI checks every pair across up to 20 drugs simultaneously — including OTCs and common supplements.

Add more drugs →

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine. For informational purposes only. Always consult your pharmacist or physician.