Propafenone + Metoprolol Interaction

Unknowninteraction on record

Description

In 4 patients, administration of metoprolol with propafenone increased the metoprolol plasma concentrations at steady state by 100% to 400%. The pharmacokinetics of propafenone was not affected by the coadministration of either propranolol or metoprolol.

Source: FDA drug label - propafenone