Protriptyline + Dextroamphetamine Saccharate%2C Amphetamine Aspartate Monohydr Interaction

Majorinteraction on record

Description

Tricyclic antidepressant may enhance activity causing striking sustained increases in d-amphetamine concentration and potentiated cardiovascular effects. Monitor frequently and adjust therapy as needed.

Mechanism

Enhanced sympathomimetic activity and increased amphetamine concentration in brain

Source: NLP:dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate and amphetamine sulfate