Does Ropinirole Interact with Carbidopa And Levodopa?
Ropinirole and Carbidopa And Levodopa have a minor drug interaction according to U.S. FDA drug labeling data. Co-administration had no effect on ropinirole steady-state pharmacokinetics. Ropinirole increased L-dopa Cmax by 20% but did not affect AUC. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Minor
- Ropinirole Class
- Nonergot Dopamine Agonist
- Carbidopa And Levodopa Class
- Aromatic Amino Acid Decarboxylation Inhibitor
- Management
- Generally manageable
- Data Source
- U.S. FDA via OpenFDA
What To Tell Your Doctor or Pharmacist
If you are taking Ropinirole and your doctor is considering prescribing Carbidopa And Levodopa (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Never stop or change either medication without first consulting your healthcare provider