Sedatives + Bupivacaine Hydrochloride And Epinephrine Bitartrate Interaction

Moderateinteraction on record

Description

Sedatives combined with local anesthetic agents may have additive CNS depressant effects. Reduced doses of sedatives are recommended.

Mechanism

Additive central nervous system depression

Source: NLP:bupivacaine hydrochloride and epinephrine bitartrate