Does Sodium Chloride Sodium Gluconate Sodium Acetate Potassium Ch Interact with Fibrates?
Sodium Chloride Sodium Gluconate Sodium Acetate Potassium Ch and Fibrates have a moderate drug interaction according to U.S. FDA drug labeling data. Solutions containing calcium in excess of normal plasma concentration may enhance clotting on contact with citrated blood. The mechanism involves calcium enhancement of clotting cascade. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Moderate
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
How This Interaction Works
The interaction between Sodium Chloride Sodium Gluconate Sodium Acetate Potassium Ch and Fibrates occurs because calcium enhancement of clotting cascade. Clinically, this means solutions containing calcium in excess of normal plasma concentration may enhance clotting on contact with citrated blood. This is classified as a moderate interaction. While it may not require stopping either medication, your healthcare provider should be aware you are taking both so they can monitor for potential effects and adjust treatment if necessary.
What To Tell Your Doctor or Pharmacist
If you are taking Sodium Chloride Sodium Gluconate Sodium Acetate Potassium Ch and your doctor is considering prescribing Fibrates (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider