Does Telotristat Ethyl Interact with Octreotide?
CDI records a major classification for Telotristat Ethyl and Octreotide. The stored summary is: Concurrent administration of short-acting octreotide significantly decreases systemic exposure of telotristat ethyl and its active metabolite. Administer short-acting octreotide at least 30 minutes after telotristat ethyl. The mechanism involves decreased absorption of telotristat ethyl. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Major
- Octreotide Class
- Somatostatin Analog
- Management
- Close medical supervision required
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Decreased absorption of telotristat ethyl
What To Tell Your Doctor or Pharmacist
If you are taking Telotristat Ethyl and your doctor is considering prescribing Octreotide (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask how frequently you should be monitored while these are co-prescribed
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider