Home›Teriflunomide›Teriflunomide + Selexipag

Does Teriflunomide Interact with Selexipag?

Teriflunomide and Selexipag have a moderate drug interaction according to U.S. FDA drug labeling data. 7 DRUG INTERACTIONS Moderate CYP2C8 inhibitors (e.g., clopidogrel, deferasirox and teriflunomide) increase exposure to the active metabolite of selexipag. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Moderate
Teriflunomide Class
Pyrimidine Synthesis Inhibitor
Selexipag Class
Prostacyclin Receptor Agonist
Management
Monitor for effects
Data Source
U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Teriflunomide and your doctor is considering prescribing Selexipag (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Ask whether any dosage adjustments are needed
  • Never stop or change either medication without first consulting your healthcare provider
💊 Teriflunomide(Aubagio)+💊 Selexipag(Selexipag)

Severity & Interaction Details

🟡
moderate
Be aware — moderate interaction
Documented interaction with manageable risk. May require dose adjustment or monitoring.
Severity scale
MinorContra
On record
Yes
Drug A class
Pyrimidine Synthesis Inhibitor
Drug B class
Prostacyclin Receptor Agonist
Source
FDA drug label - selexipag

What this means in plain English

7 DRUG INTERACTIONS Moderate CYP2C8 inhibitors (e.g., clopidogrel, deferasirox and teriflunomide) increase exposure to the active metabolite of selexipag.

About Teriflunomide and Selexipag

Teriflunomide is a Pyrimidine Synthesis Inhibitor, while Selexipag is a Prostacyclin Receptor Agonist. Teriflunomide is also sold under the brand name Aubagio. Both medications are taken by mouth. Teriflunomide additionally carries an FDA boxed warning, the FDA's strongest safety alert.

Share this result:

WhatsAppText / SMSEmail
Also share on:XFacebook
Add more drugs
Check Teriflunomide and Selexipag against your full medication list

Most patients take more than two medications. CDI checks every pair across up to 20 drugs simultaneously — including OTCs and common supplements.

Add more drugs →
Data integrity: Every interaction shown is extracted directly from official U.S. FDA drug labeling via openFDA and the U.S. National Library of Medicine (NIH) — no interactions are invented, inferred, or manually edited. Maintained by CheckDrugInteractions.com. See our methodology or report a correction at support@checkdruginteractions.com.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.