Does Tetrabenazine Interact with Carbidopa And Levodopa?
CDI records a contraindicated classification for Tetrabenazine and Carbidopa And Levodopa. The stored summary is: Use with carbidopa and levodopa is not recommended due to dopamine-depleting effects that may counteract the therapeutic benefit. The mechanism involves dopamine depletion. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Contraindicated
- Tetrabenazine Class
- Vesicular Monoamine Transporter 2 Inhibitor
- Carbidopa And Levodopa Class
- Aromatic Amino Acid Decarboxylation Inhibitor
- Management
- Do not take together
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Dopamine depletion
What To Tell Your Doctor or Pharmacist
If you are taking Tetrabenazine and your doctor is considering prescribing Carbidopa And Levodopa (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask about alternative medications that do not interact with your current regimen
- Ask how frequently you should be monitored while these are co-prescribed
- Never stop or change either medication without first consulting your healthcare provider