Does Thalidomide Interact with Amiodarone?
CDI records a moderate classification for Thalidomide and Amiodarone. The stored summary is: Amiodarone causes peripheral neuropathy and concomitant use with thalidomide can cause additive effect; should be used with caution. The mechanism involves additive peripheral neuropathy effect. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Moderate
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Additive peripheral neuropathy effect
What To Tell Your Doctor or Pharmacist
If you are taking Thalidomide and your doctor is considering prescribing Amiodarone (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider