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Does Theophylline Interact with Ropinirole?

Theophylline and Ropinirole have a minor drug interaction according to U.S. FDA drug labeling data. CYP1A2 substrate; coadministration did not alter steady-state pharmacokinetics of either drug. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Minor
Theophylline Class
Methylxanthine
Ropinirole Class
Nonergot Dopamine Agonist
Management
Generally manageable
Data Source
U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Theophylline and your doctor is considering prescribing Ropinirole (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Never stop or change either medication without first consulting your healthcare provider
💊 Theophylline(Theophylline)+💊 Ropinirole(Ropinirole)

Severity & Interaction Details

✅
minor
Generally safe — minor interaction
Low clinical significance. Routine awareness is usually sufficient.
Severity scale
MinorContra
On record
Yes
Drug A class
Methylxanthine
Drug B class
Nonergot Dopamine Agonist
Source
NLP:ropinirole

What this means in plain English

CYP1A2 substrate; coadministration did not alter steady-state pharmacokinetics of either drug.

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Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine. For informational purposes only. Always consult your pharmacist or physician.