Thiazides + Ketorolac Tromethamine Interaction

Moderateinteraction on record

Description

Ketorolac can reduce the natriuretic effect of thiazide diuretics. Close observation for signs of renal failure and diuretic efficacy is needed during concomitant therapy.

Mechanism

Inhibition of renal prostaglandin synthesis

Source: NLP:ketorolac tromethamine