Topical Local Anesthetics + Pentazocine Hydrochloride And Naloxone Hydrochloride Interaction

Majorinteraction on record

Description

Concomitant use increases risk of hypotension, respiratory depression, profound sedation, coma, and death due to additive CNS depressant effects.

Mechanism

Additive pharmacologic effect on CNS depression

Source: NLP:pentazocine and naloxone

Related drug profiles

All Topical Local Anesthetics interactions →All Pentazocine Hydrochloride And Naloxone Hydrochloride interactions →
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