Tovorafenib + Oral Contraceptives Interaction
Majorinteraction on record
Description
Tovorafenib may decrease progestin and ethinyl estradiol exposure, leading to contraceptive failure and breakthrough bleeding. Avoid coadministration or use additional nonhormonal contraception.
Mechanism
Tovorafenib is a CYP3A inducer that decreases CYP3A substrate exposure
Source: NLP:tovorafenib