Does Trandolapril Interact with Trandolapril Tablets?
Trandolapril and Trandolapril Tablets have a major drug interaction according to U.S. FDA drug labeling data. Closely monitor blood pressure, renal function and electrolytes in patients on trandolapril and other agents that affect the RAS. Avoid use of aliskiren with trandolapril in patients with renal impairment (GFR <60 ml/min). Concomitant Diuretic Therapy As with other ACE inhibitors, patients on diuretics, especially those on recently instituted diuretic therapy, may experience an excessive reduction of blood pressure after initiation of therapy with trandolapril. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Major
- Trandolapril Class
- Angiotensin Converting Enzyme Inhibitor
- Trandolapril Tablets Class
- Angiotensin Converting Enzyme Inhibitor
- Management
- Close medical supervision required
- Data Source
- U.S. FDA via OpenFDA
What To Tell Your Doctor or Pharmacist
If you are taking Trandolapril and your doctor is considering prescribing Trandolapril Tablets (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask how frequently you should be monitored while these are co-prescribed
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider