Does Ustekinumab Aekn Interact with Allergen Immunotherapy?
Ustekinumab Aekn and Allergen Immunotherapy have a moderate drug interaction according to U.S. FDA drug labeling data. Ustekinumab may decrease the protective effect of allergen immunotherapy and increase risk of allergic reaction. Caution should be exercised, particularly regarding anaphylaxis risk. The mechanism involves immunosuppressive mechanism may decrease tolerance to allergen immunotherapy. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.
- Severity
- Moderate
- Ustekinumab Aekn Class
- Interleukin-12 Antagonist
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
How This Interaction Works
The interaction between Ustekinumab Aekn and Allergen Immunotherapy occurs because immunosuppressive mechanism may decrease tolerance to allergen immunotherapy. Clinically, this means ustekinumab may decrease the protective effect of allergen immunotherapy and increase risk of allergic reaction. caution should be exercised, particularly regarding anaphylaxis risk. This is classified as a moderate interaction. While it may not require stopping either medication, your healthcare provider should be aware you are taking both so they can monitor for potential effects and adjust treatment if necessary.
What To Tell Your Doctor or Pharmacist
If you are taking Ustekinumab Aekn and your doctor is considering prescribing Allergen Immunotherapy (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider