HomeValsartan And HydrochlorothiazideValsartan And Hydrochlorothiazide + Indomethacin

Does Valsartan And Hydrochlorothiazide Interact with Indomethacin?

Valsartan And Hydrochlorothiazide and Indomethacin have a minor drug interaction according to U.S. FDA drug labeling data. No clinically significant pharmacokinetic interactions were observed when coadministered with valsartan. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Minor
Valsartan And Hydrochlorothiazide Class
Angiotensin 2 Receptor Blocker
Indomethacin Class
Nonsteroidal Anti-inflammatory Drug
Management
Generally manageable
Data Source
U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Valsartan And Hydrochlorothiazide and your doctor is considering prescribing Indomethacin (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Never stop or change either medication without first consulting your healthcare provider
💊 Valsartan And Hydrochlorothiazide(Exforge HCT)+💊 Indomethacin(Tivorbex)

Severity & Interaction Details

minor
Generally safe — minor interaction
Low clinical significance. Routine awareness is usually sufficient.
Severity scale
MinorContra
On record
Yes
Drug A class
Angiotensin 2 Receptor Blocker
Drug B class
Nonsteroidal Anti-inflammatory Drug
Source
NLP:valsartan and hydrochlorothiazide

What this means in plain English

No clinically significant pharmacokinetic interactions were observed when coadministered with valsartan.

About Valsartan And Hydrochlorothiazide and Indomethacin

Valsartan And Hydrochlorothiazide is an Angiotensin 2 Receptor Blocker, while Indomethacin is a Nonsteroidal Anti-inflammatory Drug. You may recognize them by the brand names Exforge HCT and Tivorbex. Both medications are taken by mouth. Both Valsartan And Hydrochlorothiazide and Indomethacin carry an FDA boxed warning — the agency's most serious safety designation.

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Data integrity: Every interaction shown is extracted directly from official U.S. FDA drug labeling via openFDA and the U.S. National Library of Medicine (NIH) — no interactions are invented, inferred, or manually edited. Maintained by CheckDrugInteractions.com. See our methodology or report a correction at support@checkdruginteractions.com.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.