Does Varicella Virus Vaccine Interact with Human Botulinum Neurotoxin Ab Immune Globulin?
CDI records a moderate classification for Varicella Virus Vaccine and Human Botulinum Neurotoxin Ab Immune Globulin. The stored summary is: Antibodies in BabyBIG may interfere with immune response to live varicella vaccine. Vaccination should be deferred until 6 months after BabyBIG administration. The mechanism involves passive transfer of antibodies interferes with live viral vaccine response. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Moderate
- Human Botulinum Neurotoxin Ab Immune Globulin Class
- Human Immunoglobulin G
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Passive transfer of antibodies interferes with live viral vaccine response
What To Tell Your Doctor or Pharmacist
If you are taking Varicella Virus Vaccine and your doctor is considering prescribing Human Botulinum Neurotoxin Ab Immune Globulin (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider