Does Vasopressin In 09 Sodium Chloride Interact with Clozapine?
CDI records a moderate classification for Vasopressin In 09 Sodium Chloride and Clozapine. The stored summary is: May cause diabetes insipidus, decreasing pressor and antidiuretic effects of vasopressin. Hemodynamic monitoring recommended; adjust vasopressin dose as needed. The mechanism involves diabetes insipidus-causing agents decrease pressor effect. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Moderate
- Clozapine Class
- Atypical Antipsychotic
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Diabetes insipidus-causing agents decrease pressor effect
What To Tell Your Doctor or Pharmacist
If you are taking Vasopressin In 09 Sodium Chloride and your doctor is considering prescribing Clozapine (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider