HomeVelpatasvirVelpatasvir + Emtricitabine Rilpivirine Hydrochloride And Tenofovir Alafen

Does Velpatasvir Interact with Emtricitabine Rilpivirine Hydrochloride And Tenofovir Alafen?

Velpatasvir and Emtricitabine Rilpivirine Hydrochloride And Tenofovir Alafen have a unknown drug interaction according to U.S. FDA drug labeling data. 7.8 Drugs Without Clinically Significant Interactions with ODEFSEY Based on drug interaction studies conducted with the fixed dose combination or components of ODEFSEY, no clinically significant drug interactions have been observed when ODEFSEY is combined with the following drugs: acetaminophen, atorvastatin, chlorzoxazone, digoxin, ethinyl estradiol, ledipasvir, metformin, midazolam, norethindrone, norgestimate, sildenafil, simeprevir, sofosbuvir, velpatasvir, and voxilaprevir. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This information is based on official FDA drug labeling sourced from OpenFDA and the NIH National Library of Medicine.

Severity
Unknown
Emtricitabine Rilpivirine Hydrochloride And Tenofovir Alafen Class
Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor
Management
Consult your pharmacist
Data Source
U.S. FDA via OpenFDA

What To Tell Your Doctor or Pharmacist

If you are taking Velpatasvir and your doctor is considering prescribing Emtricitabine Rilpivirine Hydrochloride And Tenofovir Alafen (or vice versa), make sure to:

  • Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
  • Ask whether the benefits of combining these medications outweigh the risks for your specific situation
  • Ask what symptoms to watch for that would indicate the interaction is causing problems
  • Never stop or change either medication without first consulting your healthcare provider
💊 Velpatasvir(Epclusa)+💊 Emtricitabine Rilpivirine Hydrochloride And Tenofovir Alafen(Odefsey)

Severity & Interaction Details

ℹ️
unknown
Interaction documented — severity unclassified
The FDA label notes an interaction but the severity is not classified in our dataset.
Severity scale
MinorContra
On record
Yes
Drug A class
Drug B class
Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor
Source
FDA drug label - emtricitabine, rilpivirine hydrochloride, and tenofovir alafenamide

What this means in plain English

7.8 Drugs Without Clinically Significant Interactions with ODEFSEY Based on drug interaction studies conducted with the fixed dose combination or components of ODEFSEY, no clinically significant drug interactions have been observed when ODEFSEY is combined with the following drugs: acetaminophen, atorvastatin, chlorzoxazone, digoxin, ethinyl estradiol, ledipasvir, metformin, midazolam, norethindrone, norgestimate, sildenafil, simeprevir, sofosbuvir, velpatasvir, and voxilaprevir.

About Velpatasvir and Emtricitabine Rilpivirine Hydrochloride And Tenofovir Alafen

Emtricitabine Rilpivirine Hydrochloride And Tenofovir Alafen is a Human Immunodeficiency Virus Nucleoside Analog Reverse Transcriptase Inhibitor. You may recognize them by the brand names Epclusa and Odefsey. Emtricitabine Rilpivirine Hydrochloride And Tenofovir Alafen is taken by mouth. Emtricitabine Rilpivirine Hydrochloride And Tenofovir Alafen additionally carries an FDA boxed warning, the FDA's strongest safety alert.

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Data integrity: Every interaction shown is extracted directly from official U.S. FDA drug labeling via openFDA and the U.S. National Library of Medicine (NIH) — no interactions are invented, inferred, or manually edited. Maintained by CheckDrugInteractions.com. See our methodology or report a correction at support@checkdruginteractions.com.

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine, supplemented with a small number of well-established interactions from curated clinical references. For informational purposes only. Always consult your pharmacist or physician.