Agonistic effects increase phenylephrine blood pressure effect.
Source: NLP:phenylephrine hydrochloride
Atropine Interactions
Brand names: Atropen Auto-Injector
Anticholinergic · Cholinergic Muscarinic Antagonist · Cholinergic Antagonists · Cholinergic Muscarinic Antagonists
Route: Intramuscular
Contraindications
4 CONTRAINDICATIONS None. None.
Pregnancy & Breastfeeding
8.1 Pregnancy Risk Summary Atropine readily crosses the placental barrier and enters fetal circulation. There are no adequate data on the developmental risk associated with the use of atropine in pregnant women. Adequate animal reproduction studies have not been conducted with atropine. In the U.S. general population, the estimated background risk of major birth defects and miscarriage in clinically recognized pregnancies is 2% to 4% and 15% to 20%, respectively.
10 interactions on record
Atropine + BarbituratesModerate
Atropine may potentiate the effect of barbiturates. Barbiturates should be used cautiously in treating convulsions from atropine exposure.
Source: NLP:atropine
Atropine + Ephedrine SulfateModerate
Augments pressor effect of ephedrine. Carefully monitor blood pressure.
Source: NLP:ephedrine sulfate
Atropine + Macimorelin AcetateModerate
Muscarinic antagonist may blunt growth hormone response to MACRILEN and impact diagnostic test accuracy. Avoid concomitant use.
Source: NLP:macimorelin acetate
Atropine + Morphine SulfateModerate
Atropine antagonizes morphine respiratory depression.
Source: NLP:morphine sulfate
Atropine + NabiloneModerate
Additive or super-additive tachycardia and drowsiness reported with concurrent use.
Source: NLP:nabilone
Pilocarpine might antagonize the anticholinergic effects of atropine, potentially reducing its therapeutic efficacy.
Source: NLP:pilocarpine hydrchloride
Pilocarpine might antagonize the anticholinergic effects of atropine, potentially reducing its therapeutic effect.
Source: NLP:pilocarpine hydrochloride
Atropine + PralidoximeModerate
Pralidoxime may potentiate atropine effect, causing earlier onset of atropinization signs (flushing, mydriasis, tachycardia, dryness of mouth/nose). Excitement and manic behavior post-consciousness recovery reported.
Source: NLP:atropine
Atropine + Trimipramine MaleateModerate
Atropine-like effects may be more pronounced in patients receiving trimipramine maleate. Particular care should be exercised when administering together.
Source: NLP:trimipramine maleate