Home›Insulin Detemir

Insulin Detemir

Also known as: Levemir

Insulin Analog

Route: Subcutaneous

38 interactions on record

Insulin Detemir has 38 known drug interactions based on U.S. FDA drug labeling data. Notable interactions include combinations with Albuterol, Alcohol, Angiotensin Ii. Patients taking Insulin Detemir should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.

Total: 38
Moderate: 36

Moderate (36)

Insulin Detemir + Albuterol— May decrease blood glucose lowering effect of insulin detemir. Dosage increases and increased glucose monitoring may be …
Insulin Detemir + Alcohol— May increase or decrease blood glucose lowering effect. Dosage adjustment and increased glucose monitoring may be requir…
Insulin Detemir + Angiotensin Ii— May increase risk of hypoglycemia. Dosage reductions and increased glucose monitoring may be required.
Insulin Detemir + Clonidine— May increase or decrease blood glucose lowering effect and may blunt signs/symptoms of hypoglycemia. Dosage adjustment a…
Insulin Detemir + Clozapine— May decrease blood glucose lowering effect of insulin detemir. Dosage increases and increased glucose monitoring may be …
Insulin Detemir + Corticosteroids— May decrease blood glucose lowering effect of insulin detemir. Dosage increases and increased glucose monitoring may be …
Insulin Detemir + Danazol— May decrease blood glucose lowering effect of insulin detemir. Dosage increases and increased glucose monitoring may be …
Insulin Detemir + Disopyramide— May increase risk of hypoglycemia. Dosage reductions and increased glucose monitoring may be required.
Insulin Detemir + Diuretics— May decrease blood glucose lowering effect of insulin detemir. Dosage increases and increased glucose monitoring may be …
Insulin Detemir + Epinephrine— May decrease blood glucose lowering effect of insulin detemir. Dosage increases and increased glucose monitoring may be …
Insulin Detemir + Estrogens— May decrease blood glucose lowering effect of insulin detemir. Dosage increases and increased glucose monitoring may be …
Insulin Detemir + Fibrates— May increase risk of hypoglycemia. Dosage reductions and increased glucose monitoring may be required.
Insulin Detemir + Fluoxetine— May increase risk of hypoglycemia. Dosage reductions and increased glucose monitoring may be required.
Insulin Detemir + Glucagon— May decrease blood glucose lowering effect of insulin detemir. Dosage increases and increased glucose monitoring may be …
Insulin Detemir + Guanethidine— May blunt signs and symptoms of hypoglycemia. Increased frequency of glucose monitoring may be required.
Insulin Detemir + Isoniazid— May decrease blood glucose lowering effect of insulin detemir. Dosage increases and increased glucose monitoring may be …
Insulin Detemir + Liraglutide— May increase risk of hypoglycemia. Dosage reductions and increased glucose monitoring may be required.
Insulin Detemir + Lithium— May increase or decrease blood glucose lowering effect. Dosage adjustment and increased glucose monitoring may be requir…
Insulin Detemir + Macrolide Antibiotics— May increase risk of hypoglycemia. Dosage reductions and increased glucose monitoring may be required.
Insulin Detemir + Mao Inhibitors— May increase risk of hypoglycemia. Dosage reductions and increased glucose monitoring may be required.
Insulin Detemir + Monoamine Oxidase Inhibitors (Maois)— May increase risk of hypoglycemia. Dosage reductions and increased glucose monitoring may be required.
Insulin Detemir + Niacin— May decrease blood glucose lowering effect of insulin detemir. Dosage increases and increased glucose monitoring may be …
Insulin Detemir + Nonselective Beta-Adrenergic Antagonists— May increase or decrease blood glucose lowering effect and may blunt signs/symptoms of hypoglycemia. Dosage adjustment a…
Insulin Detemir + Octreotide— May increase risk of hypoglycemia. Dosage reductions and increased glucose monitoring may be required.
Insulin Detemir + Olanzapine— May decrease blood glucose lowering effect of insulin detemir. Dosage increases and increased glucose monitoring may be …
Insulin Detemir + Oral Contraceptives— May decrease blood glucose lowering effect of insulin detemir. Dosage increases and increased glucose monitoring may be …
Insulin Detemir + Pentamidine— May cause hypoglycemia followed sometimes by hyperglycemia. Dosage adjustment and increased glucose monitoring may be re…
Insulin Detemir + Pentoxifylline— May increase risk of hypoglycemia. Dosage reductions and increased glucose monitoring may be required.
Insulin Detemir + Phenothiazines— May decrease blood glucose lowering effect of insulin detemir. Dosage increases and increased glucose monitoring may be …
Insulin Detemir + Pramlintide— May increase risk of hypoglycemia. Dosage reductions and increased glucose monitoring may be required.
Insulin Detemir + Protease Inhibitors— May decrease blood glucose lowering effect of insulin detemir. Dosage increases and increased glucose monitoring may be …
Insulin Detemir + Reserpine— May blunt signs and symptoms of hypoglycemia. Increased frequency of glucose monitoring may be required.
Insulin Detemir + Salicylates— May increase risk of hypoglycemia. Dosage reductions and increased glucose monitoring may be required.
Insulin Detemir + Somatropin— May decrease blood glucose lowering effect of insulin detemir. Dosage increases and increased glucose monitoring may be …
Insulin Detemir + Terbutaline— May decrease blood glucose lowering effect of insulin detemir. Dosage increases and increased glucose monitoring may be …
Insulin Detemir + Thyroid Hormones— May decrease blood glucose lowering effect of insulin detemir. Dosage increases and increased glucose monitoring may be …

Insulin Detemir + Albuterol🟡Moderate

May decrease blood glucose lowering effect of insulin detemir. Dosage increases and increased glucose monitoring may be required.

Insulin Detemir + Alcohol🟡Moderate

May increase or decrease blood glucose lowering effect. Dosage adjustment and increased glucose monitoring may be required.

Insulin Detemir + Angiotensin Ii🟡Moderate

May increase risk of hypoglycemia. Dosage reductions and increased glucose monitoring may be required.

Insulin Detemir + Clonidine🟡Moderate

May increase or decrease blood glucose lowering effect and may blunt signs/symptoms of hypoglycemia. Dosage adjustment and increased glucose monitoring required.

Insulin Detemir + Clozapine🟡Moderate

May decrease blood glucose lowering effect of insulin detemir. Dosage increases and increased glucose monitoring may be required.

Insulin Detemir + Corticosteroids🟡Moderate

May decrease blood glucose lowering effect of insulin detemir. Dosage increases and increased glucose monitoring may be required.

Insulin Detemir + Danazol🟡Moderate

May decrease blood glucose lowering effect of insulin detemir. Dosage increases and increased glucose monitoring may be required.

Insulin Detemir + Disopyramide🟡Moderate

May increase risk of hypoglycemia. Dosage reductions and increased glucose monitoring may be required.

Insulin Detemir + Diuretics🟡Moderate

May decrease blood glucose lowering effect of insulin detemir. Dosage increases and increased glucose monitoring may be required.

Insulin Detemir + Epinephrine🟡Moderate

May decrease blood glucose lowering effect of insulin detemir. Dosage increases and increased glucose monitoring may be required.

Insulin Detemir + Estrogens🟡Moderate

May decrease blood glucose lowering effect of insulin detemir. Dosage increases and increased glucose monitoring may be required.

Insulin Detemir + Fibrates🟡Moderate

May increase risk of hypoglycemia. Dosage reductions and increased glucose monitoring may be required.

Insulin Detemir + Fluoxetine🟡Moderate

May increase risk of hypoglycemia. Dosage reductions and increased glucose monitoring may be required.

Insulin Detemir + Glucagon🟡Moderate

May decrease blood glucose lowering effect of insulin detemir. Dosage increases and increased glucose monitoring may be required.

Insulin Detemir + Guanethidine🟡Moderate

May blunt signs and symptoms of hypoglycemia. Increased frequency of glucose monitoring may be required.

Insulin Detemir + Isoniazid🟡Moderate

May decrease blood glucose lowering effect of insulin detemir. Dosage increases and increased glucose monitoring may be required.

Insulin Detemir + Liraglutide🟡Moderate

May increase risk of hypoglycemia. Dosage reductions and increased glucose monitoring may be required.

Insulin Detemir + Lithium🟡Moderate

May increase or decrease blood glucose lowering effect. Dosage adjustment and increased glucose monitoring may be required.

Insulin Detemir + Macrolide Antibiotics🟡Moderate

May increase risk of hypoglycemia. Dosage reductions and increased glucose monitoring may be required.

Insulin Detemir + Mao Inhibitors🟡Moderate

May increase risk of hypoglycemia. Dosage reductions and increased glucose monitoring may be required.

Insulin Detemir + Monoamine Oxidase Inhibitors (Maois)🟡Moderate

May increase risk of hypoglycemia. Dosage reductions and increased glucose monitoring may be required.

Insulin Detemir + Niacin🟡Moderate

May decrease blood glucose lowering effect of insulin detemir. Dosage increases and increased glucose monitoring may be required.

Insulin Detemir + Nonselective Beta-Adrenergic Antagonists🟡Moderate

May increase or decrease blood glucose lowering effect and may blunt signs/symptoms of hypoglycemia. Dosage adjustment and increased glucose monitoring required.

Insulin Detemir + Octreotide🟡Moderate

May increase risk of hypoglycemia. Dosage reductions and increased glucose monitoring may be required.

Insulin Detemir + Olanzapine🟡Moderate

May decrease blood glucose lowering effect of insulin detemir. Dosage increases and increased glucose monitoring may be required.

Insulin Detemir + Oral Contraceptives🟡Moderate

May decrease blood glucose lowering effect of insulin detemir. Dosage increases and increased glucose monitoring may be required.

Insulin Detemir + Pentamidine🟡Moderate

May cause hypoglycemia followed sometimes by hyperglycemia. Dosage adjustment and increased glucose monitoring may be required.

Insulin Detemir + Pentoxifylline🟡Moderate

May increase risk of hypoglycemia. Dosage reductions and increased glucose monitoring may be required.

Insulin Detemir + Phenothiazines🟡Moderate

May decrease blood glucose lowering effect of insulin detemir. Dosage increases and increased glucose monitoring may be required.

Insulin Detemir + Pramlintide🟡Moderate

May increase risk of hypoglycemia. Dosage reductions and increased glucose monitoring may be required.

Insulin Detemir + Protease Inhibitors🟡Moderate

May decrease blood glucose lowering effect of insulin detemir. Dosage increases and increased glucose monitoring may be required.

Insulin Detemir + Reserpine🟡Moderate

May blunt signs and symptoms of hypoglycemia. Increased frequency of glucose monitoring may be required.

Insulin Detemir + Salicylates🟡Moderate

May increase risk of hypoglycemia. Dosage reductions and increased glucose monitoring may be required.

Insulin Detemir + Somatropin🟡Moderate

May decrease blood glucose lowering effect of insulin detemir. Dosage increases and increased glucose monitoring may be required.

Insulin Detemir + Terbutaline🟡Moderate

May decrease blood glucose lowering effect of insulin detemir. Dosage increases and increased glucose monitoring may be required.

Insulin Detemir + Thyroid Hormones🟡Moderate

May decrease blood glucose lowering effect of insulin detemir. Dosage increases and increased glucose monitoring may be required.

Insulin Detemir + Acetazolamideℹ️Unknown

Table 6: Clinically Significant Drug Interactions with LEVEMIR Drugs That May Increase the Risk of Hypoglycemia Drugs: Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, salicylates, somatostatin analogs (e.g., octreotide), and sulfonamide antibiotics, GLP-1 receptor agonists, DPP-4 inhibitors, SGLT-2 inhibitors.

Insulin Detemir + Somatostatinℹ️Unknown

Data sourced from U.S. FDA drug labeling via openFDA and the NIH National Library of Medicine. For informational purposes only. Always consult your pharmacist or physician.