Does Insulin Detemir Interact with Clonidine?
CDI records a moderate classification for Insulin Detemir and Clonidine. The stored summary is: May increase or decrease blood glucose lowering effect and may blunt signs/symptoms of hypoglycemia. Dosage adjustment and increased glucose monitoring required. The mechanism involves variable effect on blood glucose and hypoglycemia symptom masking. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Moderate
- Insulin Detemir Class
- Insulin Analog
- Clonidine Class
- Central alpha-2 Adrenergic Agonist
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Variable effect on blood glucose and hypoglycemia symptom masking
What To Tell Your Doctor or Pharmacist
If you are taking Insulin Detemir and your doctor is considering prescribing Clonidine (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider