Does Insulin Detemir Interact with Epinephrine?
CDI records a moderate classification for Insulin Detemir and Epinephrine. The stored summary is: May decrease blood glucose lowering effect of insulin detemir. Dosage increases and increased glucose monitoring may be required. The mechanism involves sympathomimetic agent decreases blood glucose lowering effect. Patients taking both medications should consult their healthcare provider before starting, stopping, or changing the dosage of either drug. This record was extracted from drug labeling through openFDA. NIH/NLM RxNorm is used for drug identities. The summary and severity classification are CDI's processed information, not a verbatim source quotation. Product, route, and patient circumstances matter.
- Severity
- Moderate
- Insulin Detemir Class
- Insulin Analog
- Epinephrine Class
- alpha-Adrenergic Agonist
- Management
- Monitor for effects
- Data Source
- U.S. FDA via OpenFDA
Recorded Mechanism
Sympathomimetic agent decreases blood glucose lowering effect
What To Tell Your Doctor or Pharmacist
If you are taking Insulin Detemir and your doctor is considering prescribing Epinephrine (or vice versa), make sure to:
- Inform your doctor and pharmacist of all current medications, including over-the-counter drugs and supplements
- Ask whether the benefits of combining these medications outweigh the risks for your specific situation
- Ask what symptoms to watch for that would indicate the interaction is causing problems
- Ask whether any dosage adjustments are needed
- Never stop or change either medication without first consulting your healthcare provider