Andexanet Alfa has 2 known drug interactions based on U.S. FDA drug labeling data. Of these, 1 are contraindicated combinations that should be avoided entirely. 1 are classified as major interactions requiring close medical supervision. Notable interactions include combinations with Heparin, Heparin Sodium. Patients taking Andexanet Alfa should inform their healthcare provider of all current medications — including over-the-counter drugs and supplements — to avoid potentially harmful combinations. Data sourced from OpenFDA and the NIH National Library of Medicine.
- Total
- 2
- Contraindicated
- 1
- Major
- 1
Contraindicated (1)
- Andexanet Alfa + Heparin— Unresponsiveness to unfractionated heparin following ANDEXANET ALFA administration, characterized by non-prolongation of…
Major (1)
- Andexanet Alfa + Heparin Sodium— Andexanet binds to heparin-bound antithrombin III and may reduce heparin's anticoagulant effect, potentially leading to …